Conversion to different forms of the vitamin can occur in the liver or kidney.

Metabolites are what vitamin D is converted to in the body.of Arthritis Rheum 2007;56:2143-2149).


In addition to the other health problems associated with vitamin D deficiency, there is another one. Helier University Hospital, Carsholton, and colleagues note that there is evidence that vitamin D and its metabolite 25-hydroxyvitamin D (25[OH]D), in particular, may have immunomodulatory effects.


Polyarthritis means a type of arthritis that affects many joints.. Vitamin D levels in our patients are monitored routinely.


They observed an inverse relationship between baseline levels of Astaxanthin 25(OH)D and multiple measures of disease activity. Not having enough vitamin D can make rheumatoid arthritis (and other inflammatory arthritis, possibly) symptoms worse. Many drugs taken for different diseases undergo this process.


If your vitamin D levels are low, you need replacement therapy. These findings were reported recently by researchers in the United Kingdom."


So what is the message for you if you have rheumatoid arthritis? Make sure your rheumatologist checks your vitamin D levels routinely, particularly in the winter when vitamin D levels can plummet. In the case of vitamin D, there are two active metabolites: 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D. Conversion is a common process.


According to Dr. At 1 year, baseline levels of both metabolites continued to have a significant inverse association with HAQ scores.


In the July issue of Arthritis and Rheumatism, Dr. In our practice we have noted that patients with vitamin D deficiency often have more flares than patients who have normal vitamin D levels. The researchers found that at baseline, 1,25(OH)2D levels had an inverse relationship with HAQ scores. In other words, the lower the vitamin D metabolite levels were, the more symptoms a patient had.


The investigators wanted to find out whether metabolites of vitamin D might have an influence on polyarthritis. Association between serum vitamin D metabolite levels and disease activity in patients with early inflammatory polyarthritis.


In particular, one measure- the Health Assessment Questionnaire or HAQ- is a common measure of how a patient feels. Patel, "The results of this study show that vitamin D deficiency may increase rheumatoid arthritis activity. In fact, often the metabolite is the active form of the medicine or vitamin. We need to study this further and see if giving vitamin D or more potent drugs with vitamin D activity can relieve symptoms of rheumatoid arthritis. (Patel A, Farragher T, Berry J, Bunn D, Silman A, Symmons D. The prototypical form of polyarthritis is rheumatoid arthritis.


The researchers measured serum levels of 25(OH)D and 1,25- dihydroxyvitamin D (1,25[OH]2D) in 206 patients within 6 months of the onset of symptoms of their disease. Sanjeev Patel of St

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Jiaxing Tian He Cheng Bio-technology Co., Ltd. is a professional China Nutritional Enhancers Factory and Vitamin Series https://www.thcbio.com/
Manufacturers, which committed to the production of vitamin series, polyunsaturated fatty acid series, carotenoid series and other(encapsulated) products.
The company operates strictly in accordance with ISO9001 quality system and ISO22000 food safety system, adopts advanced nano-technology, spray drying process and double encapsulation process. It is a diversified large-scale professional production base in China.

Jiaxing Tian He Cheng Bio-technology Co., Ltd. is a professional China Nutritional Enhancers Factory and Vitamin Series Manufacturers, which committed to the production of vitamin series, polyunsaturated fatty acid series, carotenoid series and other(encapsulated) products.
The company operates strictly in accordance with ISO9001 quality system and ISO22000 food safety system, adopts advanced nano-technology, spray drying process and double encapsulation process. It is a diversified large-scale professional production base in China.